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In comparison, in an Ecuadorian kindred with GH receptor deficiency and very low levels of IGF-I, rates of cancer and diabetes were markedly reduced compared to unaffected people in the same communities (39)

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Some of the phosphorylation sites that have been subjected to the greatest degree of study are Ser40, Ser44, Ser579, Ser585, Ser592, Ser616, Ser637, Ser656, Ser693, and other phosphorylation sites (Qi et al., 2019)

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