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The degradation rate and half-life (t1/2) of the drugs were determined by measuring the decrease in area under the curve (AUC) at their retention times [1]

Subcutaneous placement (correct technique) produces moderate visible swelling

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Notably, phenylpyruvate binds to palmitoyl-protein thioesterase 1 (PPT1), suppressing depalmitoylase activity, which leads to increased palmitoylation of NLRP3 and enhances inflammatory responses in diabetic wounds ( 134 )