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The shots can also reduce hospitalizations and deaths in people with a type of heart failure where the heart doesnt fill properly with blood, known as HFpEF. Several recent studies have found that the medications help to reduce the risk of heart attacks and strokes

The effort needed to optimize these regimens can be experienced as aversive, promote frustration, and generate a desire to avoid such effort, aligning with a region of the brain called the anterior midcingulate cortex, as described by Lisa Feldman Barrett and colleagues

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