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Studies have shown that it can reduce the expression of pro-inflammatory cytokines such as Tumour Necrosis Factor-alpha (TNF-) and Interleukin-6 (IL-6)

At the core of this formulation is Setria glutathione, a patented, clinically studied form of glutathione produced through a natural fermentation process in Japan

If left untreated, the deficiency can cause severe neurologic problems and blood diseases

Regardless, most patients with CSU controlled by conventional dose second generation anti-histamine therapy do not require investigation according to the European and World Allergy Organisation guidelines on urticaria [112]