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"Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways"
Because these peptides work by promoting cell growth and angiogenesis (the formation of new blood vessels), there is a concern they could speed up the growth of existing , undiagnosed tumors by feeding them a new blood supply
Inside the cells, they are reduced, particularly by the thioredoxin and glutaredoxin system, simultaneously stimulating antioxidant defense through Nrf2 activation (206)
VvGST4 (A12M): VvGST4 _A12M_fw, VvGST4 _A12M_rv, VvGST4 (C13S): VvGST4_ C13S_fw, VvGST4 _C13S_rv, VvGST4 (N108H): VvGST4 _N108H_fw, VvGST4 _N108H_rv (Supplementary Table 4) using pANT20 as template
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