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Igf1r , Igf1 receptor

Insulin-like growth factors (IGFs) are important regulators of energy metabolism homeostasis and growth ( At high concentrations, IGF-1 activates the insulin receptor ( Hussein and collaborators recently reported lowered levels of IGF-1 in the skin and blood of vitiligo patients compared to reference samples, confirming the systemic nature of vitiligo ( 7.4 Mitochondria-targeted therapy for vitiligo Existing data suggest that mitochondrial dysfunction plays a causative role in the development and progression of vitiligo