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The reduction in right ventricular end-diastolic area (RVEDA) and the improvements in right ventricular fractional area change (RVFAC) and tricuspid annular plane systolic excursion (TAPSE) suggest that semaglutide not only attenuates RV dilation but also enhances the contractile function of the RV

As a control, we verified that AITC also increased the [Ca 2+ ] i in cells transfected with the WT TRPA1 channel, but not the EV (Fig