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With semaglutide (Wegovy), two missed doses may require restarting the full titration from the lowest dose
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Moreover, the KYN pathway, which is altered in both depression and CKD, has been implicated in gut permeability and immune dysregulation, further linking the gut-brain axis with kidney dysfunction (Kearns, 2024)
10.1111/j.1365-2559.2010.03640.x 164 Rojas-ArmasJ
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