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Acute exposure to light at any point during the dark period alters Per1 expression in the core of the SCN (Shearman et al., 1997
DOI: 10.1038/s41597-024-03105-6 The solubility of a compound is highly dependent on its acid-base properties, particularly when the solution pH is within 2 log units of the compound's pKa
In 1998, diastolic HF was actually the first term used to refer to patients with congestive symptoms, EF in the normal range, and no left ventricular dilatation.39 In contrast to patients with HFrEF, most HFpEF patients have normal ventricular volumes and elevated filling pressures at rest or on exertion
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