52 , 133 In an extensive multiinstitutional study including over 5 million obese adults, GLP1RA therapy (notably liraglutide, dulaglutide, and semaglutide) was associated with significantly lower risks of Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders, alongside reduced allcause mortality
NEDA cautions that for people with active eating disorders or a history of disordered eating, these drugs can be harmful when not used for their intended purpose, when inadequately monitored or monitored by clinicians without eating disorder expertise, or when used for weight loss motivated by weight stigma. That doesnt mean GLP-1s are automatically off the table, but it does mean that this decision warrants extra care, specialist input, and close monitoring throughout
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Assessment of dapagliflozin effect on diabetic endothelial dysfunction of brachial artery (ADDENDA-BHS2 trial): rationale, design, and baseline characteristics of a randomized controlled trial
