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Combined use of the adenosine A(2A) antagonist KW-6002 with L-DOPA or with selective D1 or D2 dopamine agonists increases antiparkinsonian activity but not dyskinesia in MPTP-treated monkeys
Both substances are important tools for scientists studying various aspects of metabolism, muscle physiology and energy balance
Drug Dev Ind Pharm , 2011, 37(11): 1282-1289
The observed effect was attributed to DSePA-mediated suppression of DNA damage response pathways and, in turn, the inhibition of DNA repair in the irradiated lung cancer cells
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