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The data for 16S rRNA gene sequencing have been deposited with links to BioProject accession number PRJNA1039541 in the NCBI BioProject database ( and will be accessed upon published

103 Care for people with Down syndrome and dementia is especially challenging due to the intellectual, cognitive and communication impairments associated with Down syndrome that are present in addition to the cognitive impairments due to dementia

It improves insulin sensitivity, modestly reduces appetite, and produces a small amount of weight loss (typically 2 to 5 percent of body weight)

Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke