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[8] [9] As a precautionary measure, consistent with SmPC guidance for the drug class, retatrutide would be expected to be contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN2) Patients who are pregnant, breastfeeding, or planning pregnancy should not use retatrutide, consistent with guidance applicable to other agents in this class

Table 4 shows a comprehensive summary of treatment strategies, categorized by the level of supporting evidence to enhance clinical applicability and translational relevance

[DOI] [PMC free article] [PubMed] [Google Scholar] Shafeeq S

These two combinations act together to increase Human Growth Hormone by acting on two different families of receptors