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Molecular metabolism, 30, 72130

doi: 10.3389/fmolb.2025.1724944 Received 14 October 2025 Revised 18 November 2025 Accepted 30 November 2025 Published 18 December 2025 Volume 12 - 2025 Edited by Maria Barile, University of Bari Aldo Moro, Italy Reviewed by Anna Maria Giudetti, University of Salento, Italy Maria Tolomeo, National Research Council (CNR), Italy Updates Copyright 2025 Schrder, Jalilvand, Kahl, Kaiser and Liebau

A targeted gel formulation designed for hormone replacement therapy (HRT) to support balanced levels

It recognizes obesity as a chronic, complex disease that requires lifelong care and positions GLP-1 therapies as part of a comprehensive treatment strategy that combines medication, behavioral support focused on a healthy diet and physical activity, and long-term follow-up