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Moreover, CICR requires continual activation of VDCCs by Ca 2+ within intracellular microdomains, but not by robust Ca 2+ influx from extracellular spaces [8,15,17,24]

It simply means you have less information to work with compared to other providers

PRP therapy has been extensively studied as a minimally invasive alternative to corticosteroid injections and surgical interventions: A landmark RCT found that PRP injections resulted in significant pain relief and functional improvements compared to corticosteroids at 6-month and 1-year follow-ups (PMID: 19797698)

Comparative crossover, randomized, open-label bioequivalence study on the bioequivalence of two formulations of thioctic acid in healthy volunteers