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doi: 10.1007/978-0-387-78952-1_6 52 LarssonMRayzmanVNolteMWNickelKFBjrkqvistJJmsAet al
While emerging evidence suggests that glutathione may help reduce pigmentation and promote a brighter appearance over time, ongoing research is needed to solidify its efficacy specifically for lip lightening
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Proposed Mechanisms Preventing GABA receptor downregulation Counteracting compensatory NMDA glutamate receptor sensitization Stabilizing benzodiazepine receptor configuration (preventing shift to inverse agonist state) Upregulating GABAergic neurotransmission through pathways distinct from benzodiazepine action itself This tolerance prevention has profound clinical implications
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