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Users engaging in extended protocols should implement periodic monitoring through healthcare providers to ensure continued safety

While the test does not predict exact medication response or guarantee fungal infection outcomes, these insights can support a conversation with your provider about your baseline metabolic and immune risk profile relative to GLP-1 treatment

On the other hand, switching to an ADC with a different payload class has been shown to overcome resistance and increase antitumor efficacy: in patients with HER2+ metastatic breast cancer, switching from a TOPI inhibitor-based ADC to a microtubule inhibitor-based ADC or vice versa yielded significantly higher objective response rates and progression-free survival than sequencing two ADCs with the same payload class 248,249

They should also be used cautiously in patients with a history of pancreatitis or gastroparesis