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The Novo Nordisk-funded FLOW trial, published in the New England Journal of Medicine on 24 May 2024, randomly assigned patients with T2DM and CKD to receive subcutaneous semaglutide at a dose of 1.0mg weekly, or a placebo, to test whether treatment with semaglutide would mitigate the high risk for kidney failure, cardiovascular events and death

When you eat, your GLP-1 hormone triggers your pancreas to release insulinthe hormone that helps regulate your blood sugar levels

GLP-1 Receptor Agonists Examples: Semaglutide Brand names: Ozempic , Wegovy Tirzepatide Brand names: Mounjaro , Zepbound When to stop: Weekly injections : Stop 7 days before surgery Daily doses : Skip the dose on the day of surgery The reason to stop GLP-1 drugs prior to surgery is that they cause delayed emptying of the stomach

It also helps reduce appetite by delaying stomach emptying and promotes feelings of fullness