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Physiologically, glucagon raises blood sugar, but in this specific pharmacological context, activating the GCGR increases thermogenesis (energy expenditure)

Combined with the more efficacious injectable Zepbound and the new Employer Connect platform, Lilly possesses the clearest path to sustained market dominance in the exploding GLP-1 category

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Shao, who served as corresponding author on a JAMA study tracking sharp increases in GLP1 RA prescriptions, stresses the need for deeper research on long-term safety, effectiveness and which groups may benefit most