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The recognition that mitochondrial dysfunction is central to the aging process rather than a symptom of it has made mitochondria-targeting compounds like SS-31 core elements of advanced longevity protocols

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Given the critical roles that total BDNF and its pro- and mBDNF isoforms play in brain function, developing highly specific ELISA methods, and/or implementing indirect estimation strategies, remains essential for advancing biomarker research and achieving reliable BDNF isoform protein measurements in human samples