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this ligand is then converted to the Y2-R agonist PYY 3-36 via enzymatic cleavage by DPPIV 69,70

boulardii may play a role in resolving GI disease via improving the gut barrier integrity, a factor also implicated in IBS

Current markers [GPX4 and ACSL4 (233)] lack predictive power for ferroptosis inducer responsiveness or drug resistancethey cannot distinguish which patients will benefit from sorafenib, natural compounds [e.g., artesunate (235)], or combination regimens

This indicates poorer gout management focused on temporary relief from symptoms associated with recurrent flares, rather than long-term prevention of urate crystal deposition or joint damage