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It is hence evident that to enable an optimal pregnancy outcome, physicians should employ an individualized approach, prescribing patient-tailored Se intake within the framework of a balanced diet including, in general, an adequacy of micronutrients, particularly when this concerns expectant mothers at high risk

When H 2 O 2 increases there are several effects on one-carbon metabolism

It plays a crucial role in neutralizing free radicals

269,270 Although most superoxides stay in mitochondrial matrix, some can escape to the intermembranous space and cytosol, via anion channels when the superoxides generation is excessive