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For Type 2 diabetes, orforglipron reduced A1C levels by 1.3% to 1.6% from a baseline of 8% after 40 weeks, matching Ozempic's performance

Recent work also showed that ketones are necessary to preserve skeletal muscle mass

To improve sleep , the National Sleep Foundation recommends following a sleep schedule (sleeping and getting up at the same time every day), having a relaxing bedtime routine, keeping your bedroom cool and dark, avoiding alcohol and caffeine before bedtime, and exercising regularly

Research which looked at the genetics of nearly 28,000 people taking a GLP-1 drug also identified genetic issues in another set of receptor genes called GLP-1R and GIPR