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Repeat use in the morning and evening

RNA extraction, cDNA synthesis, and quantitative real-time polymerase chain reaction Using the RNX-Plus solution and the manufacturers instructions (Cinaclone, Iran), total RNA was extracted from adipose tissues

Mitochondrial dysfunction is another critical aspect of AD pathogenesis linked to oxidative stress

Subsequently, N-acetyl serotonin is ultimately converted into melatonin by the enzyme known as N-acylserotonin methyltransferase (ASMT) Tryptamine and 5-hydroxytryptophan are metabolized into serotonin through the activity of tryptamine 5-hydroxylase (T5H) and tryptophane decarboxylase (TDC) enzymes, respectively (175, 178, 179)