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Steps toward understanding mitochondrial Fe/S cluster biogenesis

TPP functions as a cofactor for several critical enzymes across three metabolic pathways: transketolase (TK) in the pentose phosphate pathway, pyruvate dehydrogenase (PDH) in glycolysis, and alpha-ketoglutarate dehydrogenase (AKD) in the Krebs cycle (, , )

The synthesized nanosystem was systematically characterized using TEM, element mapping, EDX spectroscopy, C MAS NMR, XRD, zeta potential, FTIR, XPS, nitrogen adsorption-desorption, and TGA analysis