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22(1):5374 The somatomedin hypothesis and insulin-like growth factor signaling in endocrine regulation Yakar S, Liu JL, Stannard B, Butler A, Accili D, Sauer B, Le Roith D., Journal of Clinical Investigation , 2001

We previously used single-patient IgG preparations from 8 individuals or pooled IgG preparations from several individuals

Several lines of evidence demonstrate that calcitriol exerts immunomodulatory and anti-proliferative effects and these effects have been hypothesized to demonstrate a role for calcitriol as a potential preventative or therapeutic in chronic auto-immune conditions such as type 1 diabetes

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