Research has shown that it counteracts the adverse effects of both L-NAME, a nitric oxide synthase blocker, and L-arginine excess
Active ingredients are protected through digestion and delivered directly into cells for maximum effectiveness
Key Characteristics MOLECULAR PROFILE Formula: C 14 H 22 CuN 6 O 4 Weight: 401.9 g/mol CAS: 89030-95-5 Structure: Gly-His-Lys (with bound copper) PHYSICAL PROPERTIES Form: Blue crystalline powder (the blue color comes from the copper) Solubility: Highly water-soluble Natural Occurrence: Found in human plasma, saliva, and urine Storage: Keep refrigerated 3646 F (28 C), protect from light Related products DSIP $55.00 $90.00Price range: $55.00 through $90.00 MOTS-c $60.00 $190.00Price range: $60.00 through $190.00
Key pathophysiologic mechanisms include: Mucosal barrier dysfunction: Impaired epithelial tight junctions allow bacterial translocation, triggering innate immune activation T-helper cell dysregulation: Predominantly Th1 and Th17 pathways drive chronic inflammation via TNF-, IL-12, IL-23 the basis for biologic therapy targets Transmural inflammation: Unlike UC (mucosal only), CD involves all layers: mucosa submucosa muscularis propria serosa Granuloma formation: Non-caseating granulomas are pathognomonic but present in only ~3050% of biopsies Fibrosis and stricture: Chronic inflammation activates myofibroblasts collagen deposition luminal narrowing obstructive symptoms Fistula formation: Transmural ulcers penetrate serosa form sinus tracts connect to adjacent bowel, bladder, vagina, or skin 7
