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"Effect of dulaglutide in promoting abstinence during smoking cessation: a single-centre, randomized, double-blind, placebo-controlled, parallel group trial." EClinicalMedicine 57 (2023)

The prescriber relies on their clinical judgment, in conjunction with the patients willingness to take a medicine that is not FDA-approved for the condition its being prescribed for, with a good understanding of the potential risks and benefits of doing so