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After 48 h, cell pellets were collected for Western blot analysis

Blood biochemistry To assess the circulating level of corticosterone, cholesterol, triglycerides, and insulin, 8-week-old male C57BL/6J mice (double-housed) on a chow diet were randomized to treatment with a single intraperitoneal injection of either 3 mg/kg psilocybin or isotonic saline ( n = 8 per group)

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However, the catabolic qualities of glucagon, notably its effect to decrease hepatic fat and circulating lipids, could be leveraged for therapeutic benefit in metabolic diseases if its diabetogenic action were mitigated