In animal models, intranasal administration of GHK-Cu improved cognitive functions, reduced amyloid plaques, and decreased inflammation in the brain, suggesting its potential as a therapeutic agent for Alzheimers disease and age-related cognitive decline 10
Therefore, targeting cellular oxidative stress through antioxidants has been suggested as a potential therapeutic option against neurological disorders, particularly using natural plant extracts
Amylin and Cagrilintide activate CGRP-like neurons in the AP that project to: Nucleus tractus solitarius (NTS) , autonomic center Parabrachial nucleus , integration of taste and satiety Hypothalamic pathways , energy balance The result: strong central appetite suppression and stabilization of satiety between meals
[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Barbariga M., Curnis F., Andolfo A., Zanardi A., Lazzaro M., Conti A., Magnani G., Volont M.A., Ferrari L., Comi G., Corti A., Alessio M