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Drawbacks: Injections require a visit to a healthcare professional, can be uncomfortable, and are often more expensive than supplements

D-dimer is a byproduct of fibrinolysis, and levels are elevated in patients with thrombosis due to the simultaneous activation of thrombotic and fibrinolytic pathways

The four subclasses of IgG [1,2,3,4] have differing capacities to engage FcRn and other immune effector molecules [129, 130], and which subclass that drives pathology differs across autoimmune diseases