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Interestingly, clinical studies in patients with neurodegenerative diseases (NDD) who do not suffer from diabetes mellitus have shown the neuroprotective effect of GLP-1RAs, independent of blood glucose levels [31]

Counterfeit drugs claim to be authentic, but could contain the wrong ingredients, contain too little, too much or no active ingredient at all or other harmful ingredients, and are illegal. As Stat News noted as part of its 2024 reporting series on the impact of weight loss drugs on the Black community, despite the explosion in popularity for GLP-1s, Black patients with diabetes are not prescribed those medications at the same rate as whites

The data from the STEP 1 Semaglutide extension showed that participants regained around two-thirds of their prior weight loss within a year after stopping treatment

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