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Furthermore, H 2 O 2 is an efficient activator of cytoplasmic NF-B [42], allowing for nuclear translocation and transcriptional activation of immunomodulatory target genes, such as pro-inflammatory cytokines TNF-, IL-1 and IL-6 [41] which have been implicated in the promotion of neuronal excitability and ictogenic events [43]

doi: 10.1186/1742-2094-9-113 71 HaukeJ.RiesslandM.LunkeS.EyupogluI