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Ask specifically whether Zepbound (tirzepatide) is covered for indication of chronic weight management, and whether prior authorization or step therapy required

Importantly, Willard and colleagues (JCI Insight, 2020) demonstrated that tirzepatide is a biased agonist at GLP-1R, favouring G protein signalling over -arrestin recruitment, a property that may attenuate receptor desensitisation during chronic exposure

Van Ellis, Mark D