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Unlike existing GLP-1 therapies, which are peptide-based and require injections, orforglipron is a synthetic, non-peptide small molecule: orally bioavailable, once-daily, and independent of food or water intake

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Para inducir la mononeuropata se realiz una intervencin quirrgica que lig el nervio citico comn cerca de su trifurcacin y luego de un perodo de recuperacin los animales fueron puestos a cuidados habituales

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