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Xiongwen Lv, orcid.org/0000-0003-2354-0168 This article was submitted to Ethnopharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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We hypothesized that loading water soluble antioxidants into the hypotonic, gel-forming vehicle could provide therapeutic scavenging of ROS in the posterior segment, a potential therapeutic opportunity for treating RP