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1 Dual agonism of GIP and GLP-1 receptors is a promising new approach currently in clinical development for the treatment of diabetes, obesity, and associated complications [1] The incretin effect defines the main physiological role of GIP and GLP-1 GIP and GLP-1 increase insulin secretion following nutrient-induced secretion from the gut (incretin effect): There is a stronger insulin secretion response to oral compared to 'isoglycemic' intravenous glucose administration due to secretion and action of incretin hormones

Journal of Food Composition and Analysis, 149, 108803

2008 [cited 2020 Apr 29];24(10):294352

I have poked a little fun at some of the more extreme longevity claims including about so-called senolytics or senolytic drugs that kill senescent cells