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Production simulations were conducted using a LFMiddle Langevin Integrator in a NPT ensemble (simulation parameters summarized in Extended Data Table 3) 77

Its popularity at the time stemmed from its perceived clinical (anti-hypertensive) effectiveness, low cost and apparently better safety profiles compared to earlier diuretics (Conway and Lauwers, 1961

If better sleep and deeper recovery are on your mind, Delta Sleep Inducing Peptide, or DSIP for short, might already be on your radar