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Lifestyle Modifications : Patients should avoid or minimize factors that accelerate bone loss, including smoking cessation and limiting alcohol consumption to no more than one drink daily for women or two for men

1c, 3c, d and Supplementary Figs

Key points Obesity is a risk factor for developing osteoarthritis (OA), gout, rheumatoid arthritis (RA), psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA), and is associated with higher disease activity and/or severity, and worse response to common treatments

For patients taking oral semaglutide (Rybelsus), specific administration instructions must be followed: take with no more than 4 ounces of plain water on an empty stomach, at least 30 minutes before eating, drinking, or taking other oral medications