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16 The aim of this paper is to review the evidence for the use of B12 in clinical practice beyond the replacement in deficiency

Since humans are not able to synthesize vitamins in B complex on their own and these vitamins are easily excreted from the body through urine, their regular intake is essential to maintain energy production, DNA/RNA synthesis/repair, genomic and non-genomic methylation as well as synthesis of numerous neurochemicals and signalling molecules

Seiwerth, S., Brcic, L., Vuletic, L., Kolenc, D., Aralica, G., Misic, M., Zenko, A., Drmic, D., Rucman, R., & Sikiric, P