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3.2.4 Ferroptosis and amyotrophic lateral sclerosis ALS is a lethal NDD characterized by progressive degeneration of upper and lower motor neurons in the cerebral cortex, brainstem, and spinal cord, leading to skeletal muscle atrophy, weakness, weight loss, dysarthria, dysphagia, paralysis, and ultimately death from respiratory failure (Urano et al., 2025)
Mechanism and Indications: Same Biology, Different Goals GLP-1 receptor agonists function through a well-characterized physiological pathway
