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doi: 10.1161/JAHA.120.016947 7 AzamMSakinahLFKartasuryaMIFibrianaAIMinuljoTTAljunidSM

Genome-wide association studies (GWAS) in humans show that the GIPR locus contributes to body weight (BW) regulation and GIPR knockout mice are protected from diet-induced obesity (DIO) 27,28,29,30,31,32

Patients are encouraged to work with healthcare providers to develop a comprehensive plan that includes lifestyle modifications, ensuring a holistic approach to weight management and health improvement

The appetite-regulating effects of GLP-1 medications can counteract the increased hunger and cravings driven by hormonal fluctuations