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Although the etiology of depression has not been fully elucidated, current scientific data emphasize the role of neurotrophic factors deficiencies, disturbed homeostasis between the nervous system and the immune and endocrine systems, as well as disturbances in brain energy metabolism and dysfunctions in the gut-brain axis as important factors in the pathogenesis of this neuropsychiatric disorder

In spontaneously hypertensive rats, GLP-1 treatment mediates renal vasodilation and attenuates renal autoregulatory responses [68]

doi: 10.1055/s-2004-826175 141 MeierJJGallwitzBSalmenSGoetzeOHolstJJSchmidtWEet al