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Models on placental clearance index prediction for diverse drugs and chemicals have been proposed using the ex vivo diffusion technique, QSAR-based studies, and multivariate data analysis (MVDA) [102,103,104,105,106,107,136]

Efficacy of daily low-dose sildenafil for treating interstitial cystitis: results of a randomized, double-blind, placebo-controlled trial treatment of interstitial cystitis/painful bladder syndrome with low-dose sildenafil