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46 The data from these mice, similar to those subjected to a transient increase in gut permeability, suggest that under conditions of compromised gut permeability, there are adaptive immune components activated in response to the hyperactivated immune system, and that these immune compensatory mechanisms may help provide resistance to colitis

Some patients and clinicians choose a slow taper schedulefor example, spacing injections further apart over 2 to 3 weeksto allow the body to adjust more gently