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Both formulations are administered as subcutaneous injections once weekly, but they use different delivery devices

Although the pen is not approved for routine clinical use and remains under clinical investigation, understanding how they are administered is important

Yamamoto & Ishihara, Stability of Glutathione in Solution (1994), DOI 10.1007/978-1-4615-2674-2_62 Supports the general stability profile of glutathione in aqueous solution

NICE's published technology appraisals for semaglutide (Wegovy) and tirzepatide (Mounjaro) for weight management provide a framework illustrating the appraisal criteria against which retatrutide would be assessed