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Ferreira SC, Bruns RE, Ferreira HS, Matos GD, David JM, Brandao GC, da Silva EP, Portugal LA, Dos Reis PS, Souza AS, Dos Santos WN (2007) Box-Behnken design: an alternative for the optimization of analytical methods
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GHRP-6 and Wound Healing Research In excisional full-thickness wound models in Wistar rats, topical GHRP-6 at 400 g/mL accelerated wound closure from the first 24 hours post-injury, significantly reduced proinflammatory and profibrogenic cytokines, and in a rabbit ear hypertrophic scar model dramatically reduced the onset of exuberant scarring by activating PPAR and downregulating fibrogenic cytokines