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however, results derived from large scale randomised clinical trials have been disappointing as no positive effects were demonstrated

Jan 3, 2026 Dark circles under eyes create persistent cosmetic concern affecting appearance across all ages and skin types, with multiple underlying causes including thin periorbital skin revealing underlying vasculature, hyperpigmentation from melanin accumulation, shadows from volume loss and fat pad descent, and fluid retention creating puffiness accentuating darkness

M.et al (2012)

The most common thyroid disorders include: Hypothyroidism Hyperthyroidism Graves Disease Thyroiditis Postpartum Thyroiditis Goiter Thyroid Nodules Thyroid Cancer Hypothyroidism Hypothyroidism, also referred to as underactive thyroid, occurs when the thyroid does not produce enough of the thyroid hormones