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The six groups included (i) control group, (ii) stress group, (iii) group with DSIP one hour before stress experiments, (iv) DSIP 24 hours before stress experiments, (v) DSIP one hour before the last stress experiment and (vi) DSIP 24 hours before the last stress experiment

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They conjugated Iso1 to gold nanoparticles loaded with IL-12 (Iso1/Au/IL-12) and evaluated this nanoformulation in murine models of PCa

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