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To the reaction mixture, containing deprotected pentapeptide hydrochloride and Pd(OH) 2 , was added a solution of Z-Asp( O t Bu)-OPfp (26.3 g) in THF (150 mL), and the resulting mixture was stirred for 1 h at r.t

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In contrast, more severe toxicity was observed when rat or human liver slices were incubated with AMAP than when mouse liver slices were incubated with the compound, or when rat and human liver slices were incubated with acetaminophen